We describe the production of collagen fibre bundles through a multi-strand. semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). NHS (N-hydroxysuccinimide) combination was considered. https://cosmeticssquadets.shop/product-category/hand-tools/
The process of EDC-NHS cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment
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