We previously showed that extracellular ATP and hydrogen sulfide (H2S). a recently discovered gasotransmitter. are both triggering the nociceptive firing in trigeminal nociceptors implicated in migraine pain. ATP contributes to meningeal nociception by activating the P2X3 subunit-containing receptors whereas H2S operates mainly via TRP receptors. https://countryscenesaddleryandpetsuppliers.shop/product-category/horse-tack/